An evolutionary approach for the identification of a cocktail of drugs for the treatment of Chagas disease

This research will focus on trying to solve the problem of a lack of effective treatments for Chagas disease once entering in its chronic phase. We will develop a computational comparative genomics approach to identify cocktails of FDA (Food and Drugs Administration) approved drugs that could potent...

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Main Author: Yubero Rodríguez, Víctor Andrés (author)
Format: article
Language:English
Published: 2017
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Online Access:http://hdl.handle.net/20.500.14066/2785
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author Yubero Rodríguez, Víctor Andrés
author_browse Yubero Rodríguez, Víctor Andrés
author_facet Yubero Rodríguez, Víctor Andrés
author_role author
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dc.contributor.advisor.none.fl_str_mv Burgos Edwards, Alberto Javier
dc.contributor.other.es.fl_str_mv Universidad Católica "Nuestra Señora de la Asunción" (PY)
dc.creator.none.fl_str_mv Yubero Rodríguez, Víctor Andrés
dc.date.accessioned.none.fl_str_mv 2022-04-04T22:55:16Z
dc.date.available.none.fl_str_mv 2022-04-04T22:55:16Z
dc.date.issued.none.fl_str_mv 2017
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.14066/2785
dc.language.iso.es.fl_str_mv eng
dc.relation.projectCONACYT.es.fl_str_mv 14-INV-088
dc.rights.accessRights.es.fl_str_mv info:eu-repo/semantics/openAccess
dc.subject.classification.es.fl_str_mv 6. Producción y tecnología industrial
dc.subject.other.es.fl_str_mv CHAGAS
COCKTAIL OF DRUGS
COMPUTATIONAL COMPARATIVE
FARMACOLOGIA
DROGAS
dc.title.es.fl_str_mv An evolutionary approach for the identification of a cocktail of drugs for the treatment of Chagas disease
dc.type.es.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
description This research will focus on trying to solve the problem of a lack of effective treatments for Chagas disease once entering in its chronic phase. We will develop a computational comparative genomics approach to identify cocktails of FDA (Food and Drugs Administration) approved drugs that could potentially work for the treatment of Chagas disease. In the following section we will introduce biological concepts as well in order to understand appropriately the aim of our work.
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publishDate 2017
publishDateSort 2017
repository.mail.fl_str_mv repositorio.institucional@conacyt.gov.py
repository.name.fl_str_mv Repositorio Institucional CONACYT
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spelling Burgos Edwards, Alberto Javier851600a8103d73-86cb-458f-b342-e22517fed4b6600Universidad Católica "Nuestra Señora de la Asunción" (PY)2022-04-04T22:55:16Z2022-04-04T22:55:16Z2017http://hdl.handle.net/20.500.14066/2785This research will focus on trying to solve the problem of a lack of effective treatments for Chagas disease once entering in its chronic phase. We will develop a computational comparative genomics approach to identify cocktails of FDA (Food and Drugs Administration) approved drugs that could potentially work for the treatment of Chagas disease. In the following section we will introduce biological concepts as well in order to understand appropriately the aim of our work.Consejo Nacional de Ciencia y TecnologíaPROCIENCIAeng6. Producción y tecnología industrialCHAGASCOCKTAIL OF DRUGSCOMPUTATIONAL COMPARATIVEFARMACOLOGIADROGASAn evolutionary approach for the identification of a cocktail of drugs for the treatment of Chagas diseaseinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion11614-INV-088info:eu-repo/semantics/openAccessYubero Rodríguez, Víctor AndrésORIGINAL14-inv-088art1.pdf14-inv-088art1.pdfapplication/pdf1388798http://repositorio.conacyt.gov.py/bitstream/20.500.14066/2785/1/14-inv-088art1.pdfc6232d460d69b3ccb61e62aaa2adbfc1MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81698http://repositorio.conacyt.gov.py/bitstream/20.500.14066/2785/2/license.txt858b22fda432bd774e469302988c1974MD52TEXT14-inv-088art1.pdf.txt14-inv-088art1.pdf.txtExtracted texttext/plain47868http://repositorio.conacyt.gov.py/bitstream/20.500.14066/2785/4/14-inv-088art1.pdf.txta7630ac91aa63ad8a1878892fb03fe25MD54THUMBNAIL14-inv-088art1.pdf.jpg14-inv-088art1.pdf.jpgIM Thumbnailimage/jpeg7564http://repositorio.conacyt.gov.py/bitstream/20.500.14066/2785/5/14-inv-088art1.pdf.jpge06a5bd37b0837eea8ce7338652fc3caMD5520.500.14066/2785oai:repositorio.conacyt.gov.py:20.500.14066/27852026-02-12 19:30:22.791Repositorio Institucional CONACYTrepositorio.institucional@conacyt.gov.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
spellingShingle An evolutionary approach for the identification of a cocktail of drugs for the treatment of Chagas disease
Yubero Rodríguez, Víctor Andrés
6. Producción y tecnología industrial
CHAGAS
COCKTAIL OF DRUGS
COMPUTATIONAL COMPARATIVE
FARMACOLOGIA
DROGAS
status_str publishedVersion
title An evolutionary approach for the identification of a cocktail of drugs for the treatment of Chagas disease
title_full An evolutionary approach for the identification of a cocktail of drugs for the treatment of Chagas disease
title_fullStr An evolutionary approach for the identification of a cocktail of drugs for the treatment of Chagas disease
title_full_unstemmed An evolutionary approach for the identification of a cocktail of drugs for the treatment of Chagas disease
title_short An evolutionary approach for the identification of a cocktail of drugs for the treatment of Chagas disease
title_sort An evolutionary approach for the identification of a cocktail of drugs for the treatment of Chagas disease
topic 6. Producción y tecnología industrial
CHAGAS
COCKTAIL OF DRUGS
COMPUTATIONAL COMPARATIVE
FARMACOLOGIA
DROGAS
url http://hdl.handle.net/20.500.14066/2785