An evolutionary approach for the identification of a cocktail of drugs for the treatment of Chagas disease
This research will focus on trying to solve the problem of a lack of effective treatments for Chagas disease once entering in its chronic phase. We will develop a computational comparative genomics approach to identify cocktails of FDA (Food and Drugs Administration) approved drugs that could potent...
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| Format: | article |
| Language: | English |
| Published: |
2017
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.14066/2785 |
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| _version_ | 1870885381947260928 |
|---|---|
| author | Yubero Rodríguez, Víctor Andrés |
| author_browse | Yubero Rodríguez, Víctor Andrés |
| author_facet | Yubero Rodríguez, Víctor Andrés |
| author_role | author |
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| bitstream.url.fl_str_mv | http://repositorio.conacyt.gov.py/bitstream/20.500.14066/2785/1/14-inv-088art1.pdf http://repositorio.conacyt.gov.py/bitstream/20.500.14066/2785/2/license.txt http://repositorio.conacyt.gov.py/bitstream/20.500.14066/2785/4/14-inv-088art1.pdf.txt http://repositorio.conacyt.gov.py/bitstream/20.500.14066/2785/5/14-inv-088art1.pdf.jpg |
| dc.contributor.advisor.none.fl_str_mv | Burgos Edwards, Alberto Javier |
| dc.contributor.other.es.fl_str_mv | Universidad Católica "Nuestra Señora de la Asunción" (PY) |
| dc.creator.none.fl_str_mv | Yubero Rodríguez, Víctor Andrés |
| dc.date.accessioned.none.fl_str_mv | 2022-04-04T22:55:16Z |
| dc.date.available.none.fl_str_mv | 2022-04-04T22:55:16Z |
| dc.date.issued.none.fl_str_mv | 2017 |
| dc.identifier.uri.none.fl_str_mv | http://hdl.handle.net/20.500.14066/2785 |
| dc.language.iso.es.fl_str_mv | eng |
| dc.relation.projectCONACYT.es.fl_str_mv | 14-INV-088 |
| dc.rights.accessRights.es.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.subject.classification.es.fl_str_mv | 6. Producción y tecnología industrial |
| dc.subject.other.es.fl_str_mv | CHAGAS COCKTAIL OF DRUGS COMPUTATIONAL COMPARATIVE FARMACOLOGIA DROGAS |
| dc.title.es.fl_str_mv | An evolutionary approach for the identification of a cocktail of drugs for the treatment of Chagas disease |
| dc.type.es.fl_str_mv | info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| description | This research will focus on trying to solve the problem of a lack of effective treatments for Chagas disease once entering in its chronic phase. We will develop a computational comparative genomics approach to identify cocktails of FDA (Food and Drugs Administration) approved drugs that could potentially work for the treatment of Chagas disease. In the following section we will introduce biological concepts as well in order to understand appropriately the aim of our work. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | CONACYT_08ac48c7eb6b8ca3133b164ac42a7569 |
| language | eng |
| network_acronym_str | CONACYT |
| network_name_str | Repositorio Institucional CONACYT |
| oai_identifier_str | oai:repositorio.conacyt.gov.py:20.500.14066/2785 |
| publishDate | 2017 |
| publishDateSort | 2017 |
| repository.mail.fl_str_mv | repositorio.institucional@conacyt.gov.py |
| repository.name.fl_str_mv | Repositorio Institucional CONACYT |
| repository_id_str | |
| spelling | Burgos Edwards, Alberto Javier851600a8103d73-86cb-458f-b342-e22517fed4b6600Universidad Católica "Nuestra Señora de la Asunción" (PY)2022-04-04T22:55:16Z2022-04-04T22:55:16Z2017http://hdl.handle.net/20.500.14066/2785This research will focus on trying to solve the problem of a lack of effective treatments for Chagas disease once entering in its chronic phase. We will develop a computational comparative genomics approach to identify cocktails of FDA (Food and Drugs Administration) approved drugs that could potentially work for the treatment of Chagas disease. In the following section we will introduce biological concepts as well in order to understand appropriately the aim of our work.Consejo Nacional de Ciencia y TecnologíaPROCIENCIAeng6. Producción y tecnología industrialCHAGASCOCKTAIL OF DRUGSCOMPUTATIONAL COMPARATIVEFARMACOLOGIADROGASAn evolutionary approach for the identification of a cocktail of drugs for the treatment of Chagas diseaseinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion11614-INV-088info:eu-repo/semantics/openAccessYubero Rodríguez, Víctor AndrésORIGINAL14-inv-088art1.pdf14-inv-088art1.pdfapplication/pdf1388798http://repositorio.conacyt.gov.py/bitstream/20.500.14066/2785/1/14-inv-088art1.pdfc6232d460d69b3ccb61e62aaa2adbfc1MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81698http://repositorio.conacyt.gov.py/bitstream/20.500.14066/2785/2/license.txt858b22fda432bd774e469302988c1974MD52TEXT14-inv-088art1.pdf.txt14-inv-088art1.pdf.txtExtracted texttext/plain47868http://repositorio.conacyt.gov.py/bitstream/20.500.14066/2785/4/14-inv-088art1.pdf.txta7630ac91aa63ad8a1878892fb03fe25MD54THUMBNAIL14-inv-088art1.pdf.jpg14-inv-088art1.pdf.jpgIM Thumbnailimage/jpeg7564http://repositorio.conacyt.gov.py/bitstream/20.500.14066/2785/5/14-inv-088art1.pdf.jpge06a5bd37b0837eea8ce7338652fc3caMD5520.500.14066/2785oai:repositorio.conacyt.gov.py:20.500.14066/27852026-02-12 19:30:22.791Repositorio Institucional CONACYTrepositorio.institucional@conacyt.gov.pyQWwgYWNlcHRhciBlc3RhIGxpY2VuY2lhLCB1c3RlZCBjb21vIGF1dG9yIHkgcHJvcGlldGFyaW8gZGUgbG9zIGRlcmVjaG9zIGRlIHByb3BpZWRhZCBpbnRlbGVjdHVhbCBkZSBzdSBvYnJhIG90b3JnYSBhbCBSZXBvc2l0b3JpbyBJbnN0aXR1Y2lvbmFsIENPTkFDWVQgZWwgZGVyZWNobyBubyBleGNsdXNpdm8gZGUgcmVwcm9kdWNjacOzbiB5IGRpc3RyaWJ1Y2nDs24gZGUgc3Ugb2JyYSBlbiBjdWFscXVpZXIgZm9ybWF0byB5IG1lZGlvLgoKQWNlcHRhIHF1ZSwgc2luIG1vZGlmaWNhciBlbCBjb250ZW5pZG8sIHNlIHB1ZWRhIGNvbnZlcnRpciBzdSBvYnJhIGEgb3RybyBmb3JtYXRvIGNvbiBmaW5lcyBkZSBwcmVzZXJ2YWNpw7NuLiBBc8OtIG1pc21vLCBhY2VwdGEgcXVlIHNlIHB1ZWRhIGNvbnNlcnZhciBtw6FzIGRlIHVuYSBjb3BpYSBwb3IgbW90aXZvcyBkZSBzZWd1cmlkYWQgeSBwcmVzZXJ2YWNpw7NuLgoKVXN0ZWQgZGVjbGFyYSBxdWUgZWwgdHJhYmFqbyBwcmVzZW50YWRvIGVzIG9yaWdpbmFsIHkgcXVlIGN1ZW50YSBjb24gbGEgcG90ZXN0YWQgcGFyYSBvdG9yZ2FyIGxvcyBkZXJlY2hvcyBkZXRhbGxhZG9zIGVuIGVzdGEgbGljZW5jaWEuIFRhbWJpw6luIGRlY2xhcmEgcXVlIHN1IG9icmEgbm8gaW5mcmluZ2UgbG8gZXN0YWJsZWNpZG8gZW4gbGEgdmlnZW50ZSBsZWdpc2xhY2nDs24gc29icmUgcHJvcGllZGFkIGludGVsZWN0dWFsLgoKU2kgbGEgb2JyYSBjb250aWVuZSBtYXRlcmlhbCBwYXJhIGVsIGN1YWwgbm8gdGllbmUgZGVyZWNob3MgZGUgYXV0b3IsIHVzdGVkIGRlY2xhcmEgcXVlIGhhIG9idGVuaWRvIGxvcyBwZXJtaXNvcyBuZWNlc2FyaW9zIGRlbCBwcm9waWV0YXJpbyBwYXJhIG90b3JnYXIgYWwgUmVwb3NpdG9yaW8gSW5zdGl0dWNpb25hbCBDT05BQ1lUIGxvcyBkZXJlY2hvcyByZXF1ZXJpZG9zIHBvciBlc3RhIGxpY2VuY2lhLCB5IHF1ZSBkaWNobyBtYXRlcmlhbCBkZSBwcm9waWVkYWQgZGUgdGVyY2Vyb3MgZXN0w6EgY2xhcmFtZW50ZSBpZGVudGlmaWNhZG8geSByZWNvbm9jaWRvIGRlbnRybyBkZWwgY29udGVuaWRvIGRlIGxhIG9icmEuCgpTaSBsYSBvYnJhIHF1ZSBkZXBvc2l0YSBoYSBzaWRvIHBhdHJvY2luYWRhIG8gZmluYW5jaWFkYSBwb3IgdW5hIG9yZ2FuaXphY2nDs24sIHVzdGVkIGRlY2xhcmEgcXVlIGhhIGN1bXBsaWRvIGNvbiBsYXMgb2JsaWdhY2lvbmVzIHJlcXVlcmlkYXMgcG9yIHRhbCBhY3VlcmRvLgoKU2kgZWwgZG9jdW1lbnRvIHNlIGJhc2EgZW4gdW5hIG9icmEgcXVlIGhhIHNpZG8gcGF0cm9jaW5hZGEgbyBhcG95YWRhIHBvciB1bmEgYWdlbmNpYSB1IG9yZ2FuaXphY2nDs24sIHNlIHByZXN1cG9uZSBxdWUgc2UgaGEgY3VtcGxpZG8gY29uIGN1YWxxdWllciBkZXJlY2hvIGRlIHJldmlzacOzbiB1IG90cmFzIG9ibGlnYWNpb25lcyByZXF1ZXJpZGFzIHBvciBlc3RlIGNvbnRyYXRvIG8gYWN1ZXJkby4KCkVsIFJlcG9zaXRvcmlvIEluc3RpdHVjaW9uYWwgQ09OQUNZVCBpZGVudGlmaWNhcsOhIGNsYXJhbWVudGUgc3UvcyBub21icmUvcyBjb21vIGVsL2xvcyBhdXRvci9lcyBvIHByb3BpZXRhcmlvL3MgZGUgbG9zIGRlcmVjaG9zIGRlbCBkb2N1bWVudG8sIHkgbm8gaGFyw6EgbmluZ3VuYSBhbHRlcmFjacOzbiBkZSBzdSBkb2N1bWVudG8gZGlmZXJlbnRlIGEgbGFzIHBlcm1pdGlkYXMgZW4gZXN0YSBsaWNlbmNpYS4K |
| spellingShingle | An evolutionary approach for the identification of a cocktail of drugs for the treatment of Chagas disease Yubero Rodríguez, Víctor Andrés 6. Producción y tecnología industrial CHAGAS COCKTAIL OF DRUGS COMPUTATIONAL COMPARATIVE FARMACOLOGIA DROGAS |
| status_str | publishedVersion |
| title | An evolutionary approach for the identification of a cocktail of drugs for the treatment of Chagas disease |
| title_full | An evolutionary approach for the identification of a cocktail of drugs for the treatment of Chagas disease |
| title_fullStr | An evolutionary approach for the identification of a cocktail of drugs for the treatment of Chagas disease |
| title_full_unstemmed | An evolutionary approach for the identification of a cocktail of drugs for the treatment of Chagas disease |
| title_short | An evolutionary approach for the identification of a cocktail of drugs for the treatment of Chagas disease |
| title_sort | An evolutionary approach for the identification of a cocktail of drugs for the treatment of Chagas disease |
| topic | 6. Producción y tecnología industrial CHAGAS COCKTAIL OF DRUGS COMPUTATIONAL COMPARATIVE FARMACOLOGIA DROGAS |
| url | http://hdl.handle.net/20.500.14066/2785 |