Subclonal mutation selection in mouse lymphomagenesis identifies known cancer loci and suggests novel candidates

Determining whether recurrent but rare cancer mutations are bona fide driver mutations remains a bottleneck in cancer research. Here we present the most comprehensive analysis of murine leukemia virus-driven lymphomagenesis produced to date, sequencing 700,000 mutations from >500 malignancies collec...

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Bibliographic Details

Main Author:	Webster, Philip (author)
Other Authors:	Dawes, Joanna C. (author), Dewchand, Hamlata (author), Takacs, Katalin (author), Ladarola, Barbara (author), Bolt, Bruce J. (author), Caceres, Juan J. (author), Kaczor, Jakub (author), Dharmalingam, Gopuraja (author), Dore, Marian (author), Game, Laurence (author), Adejumo, Thomas (author), Elliott, James (author), Naresh, Kikkeri (author), Karimi, Mohammad (author), Rekopoulou, Katerina (author), Tan, Ge (author), Burgos Edwards, Alberto Javier (author), Uren, Anthony G. (author)
Format:	article
Language:	English
Published:	2018
Subjects:	1301 I+D en relación con las Ciencias naturales SUBCLONAL MUTATION GENOTYPIC AND PHENOTYPIC FEATURES CANCER GENES LEUCEMIA BIOLOGIA MOLECULAR BIOLOGIA
Online Access:	http://hdl.handle.net/20.500.14066/2833
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