Cytokine Removal and Immunomodulation in COVID-19 Severe Pulmonary Respiratory Infection
Coronavirus infection produces a cytokine storm in some patients, developing a moderate to severe clinical condition that is associated with increased mortality mainly because of severe pulmonary involvement. Elevated levels of IL-6 have been found in non-survivor patients. In these patients, cleara...
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| Үндсэн зохиолч: | |
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| Бусад зохиолчид: | , |
| Формат: | article |
| Хэл сонгох: | англи |
| Хэвлэсэн: |
2020
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| Нөхцлүүд: | |
| Онлайн хандалт: | https://zenodo.org/record/4484015 |
| Шошгууд: |
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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| Тойм: | Coronavirus infection produces a cytokine storm in some patients, developing a moderate to severe clinical condition that is associated with increased mortality mainly because of severe pulmonary involvement. Elevated levels of IL-6 have been found in non-survivor patients. In these patients, clearance of cytokines with extracorporeal therapies, Pulse High- Volume Hemofiltration together with adsorption columns Cytosorb, in short periods of time for 1 to 3 days, could help remove inflammatory cytokines allowing a downregulation of the inflammatory response; and, at the same time, treatment with low dose steroids, could give an opportunity for the host to reach homeostasis, decreasing lung damage and improving survival |
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