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Combining Interactomes from Multiple Organisms: a Case Study on Human-Mouse

The amount and quality of available data on different organisms varies greatly. While model organisms benefit from extensive experimental studies, there is often a lack of detailed experimental data for more specific organisms. Additionally, even among model organisms there are noticeable difference...

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I tiakina i:
Kaituhi matua: Cáceres Silva, Juan José (author)
Ētahi atu kaituhi: Burgos Edwards, Alberto Javier (author)
Hōputu: article
Reo:Ingarihi
I whakaputaina: 2016
Ngā marau:
1301 I+D en relación con las Ciencias naturales
GENE NETWORK
BIOLOGIA MOLECULAR
STUDY ON HUMAN-MOUSE
BIOLOGIA
Urunga tuihono:http://hdl.handle.net/20.500.14066/2997
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author Cáceres Silva, Juan José
author2 Burgos Edwards, Alberto Javier
author2_role author
author_browse Burgos Edwards, Alberto Javier
Cáceres Silva, Juan José
author_facet Cáceres Silva, Juan José
Burgos Edwards, Alberto Javier
author_role author
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bitstream.checksumAlgorithm.fl_str_mv MD5
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bitstream.url.fl_str_mv http://repositorio.conacyt.gov.py/bitstream/20.500.14066/2997/1/14-inv-088art8.pdf
http://repositorio.conacyt.gov.py/bitstream/20.500.14066/2997/2/license.txt
http://repositorio.conacyt.gov.py/bitstream/20.500.14066/2997/3/14-inv-088art8.pdf.txt
dc.contributor.other.es.fl_str_mv University of London (UK)
dc.creator.none.fl_str_mv Cáceres Silva, Juan José
Burgos Edwards, Alberto Javier
dc.date.accessioned.none.fl_str_mv 2022-04-21T02:22:39Z
dc.date.available.none.fl_str_mv 2022-04-21T02:22:39Z
dc.date.issued.none.fl_str_mv 2016
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.14066/2997
dc.language.iso.es.fl_str_mv eng
dc.relation.projectCONACYT.es.fl_str_mv 14-INV-088
dc.rights.accessRights.es.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.copyright.es.fl_str_mv © 2016 IEEE
dc.subject.classification.es.fl_str_mv 1301 I+D en relación con las Ciencias naturales
dc.subject.ocde.es.fl_str_mv BIOLOGIA
dc.subject.other.es.fl_str_mv GENE NETWORK
BIOLOGIA MOLECULAR
STUDY ON HUMAN-MOUSE
dc.title.es.fl_str_mv Combining Interactomes from Multiple Organisms: a Case Study on Human-Mouse
dc.type.es.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
description The amount and quality of available data on different organisms varies greatly. While model organisms benefit from extensive experimental studies, there is often a lack of detailed experimental data for more specific organisms. Additionally, even among model organisms there are noticeable differences in the amount and type of data available, due to the different suitability of experiments in different organisms. The combination of interactomes for closely related species, represents a viable tool to increase the amount of protein- protein interaction data for a given organism. The Human-Mouse case of study is particularly relevant, as many experiments cannot be carried out on humans. This paper describes a general method to construct a combined interactome from different organisms.
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publishDate 2016
publishDateSort 2016
repository.mail.fl_str_mv repositorio.institucional@conacyt.gov.py
repository.name.fl_str_mv Repositorio Institucional CONACYT
repository_id_str
rights_invalid_str_mv © 2016 IEEE
spelling 228600851600University of London (UK)2022-04-21T02:22:39Z2022-04-21T02:22:39Z2016http://hdl.handle.net/20.500.14066/2997The amount and quality of available data on different organisms varies greatly. While model organisms benefit from extensive experimental studies, there is often a lack of detailed experimental data for more specific organisms. Additionally, even among model organisms there are noticeable differences in the amount and type of data available, due to the different suitability of experiments in different organisms. The combination of interactomes for closely related species, represents a viable tool to increase the amount of protein- protein interaction data for a given organism. The Human-Mouse case of study is particularly relevant, as many experiments cannot be carried out on humans. This paper describes a general method to construct a combined interactome from different organisms.Consejo Nacional de Ciencia y TecnologíaPROCIENCIAeng1301 I+D en relación con las Ciencias naturalesGENE NETWORKBIOLOGIA MOLECULARSTUDY ON HUMAN-MOUSEBIOLOGIACombining Interactomes from Multiple Organisms: a Case Study on Human-Mouseinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion14-INV-088info:eu-repo/semantics/openAccess© 2016 IEEECáceres Silva, Juan JoséBurgos Edwards, Alberto JavierORIGINAL14-inv-088art8.pdf14-inv-088art8.pdfapplication/pdf98309http://repositorio.conacyt.gov.py/bitstream/20.500.14066/2997/1/14-inv-088art8.pdf2d7f5164adc6f60043300ac23e671b04MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81698http://repositorio.conacyt.gov.py/bitstream/20.500.14066/2997/2/license.txt858b22fda432bd774e469302988c1974MD52TEXT14-inv-088art8.pdf.txt14-inv-088art8.pdf.txtExtracted texttext/plain29691http://repositorio.conacyt.gov.py/bitstream/20.500.14066/2997/3/14-inv-088art8.pdf.txtbcf5da70a739b61387d218a2865402c1MD5320.500.14066/2997oai:repositorio.conacyt.gov.py:20.500.14066/29972026-02-12 19:30:22.993Repositorio Institucional CONACYTrepositorio.institucional@conacyt.gov.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
spellingShingle Combining Interactomes from Multiple Organisms: a Case Study on Human-Mouse
Cáceres Silva, Juan José
1301 I+D en relación con las Ciencias naturales
GENE NETWORK
BIOLOGIA MOLECULAR
STUDY ON HUMAN-MOUSE
BIOLOGIA
status_str publishedVersion
title Combining Interactomes from Multiple Organisms: a Case Study on Human-Mouse
title_full Combining Interactomes from Multiple Organisms: a Case Study on Human-Mouse
title_fullStr Combining Interactomes from Multiple Organisms: a Case Study on Human-Mouse
title_full_unstemmed Combining Interactomes from Multiple Organisms: a Case Study on Human-Mouse
title_short Combining Interactomes from Multiple Organisms: a Case Study on Human-Mouse
title_sort Combining Interactomes from Multiple Organisms: a Case Study on Human-Mouse
topic 1301 I+D en relación con las Ciencias naturales
GENE NETWORK
BIOLOGIA MOLECULAR
STUDY ON HUMAN-MOUSE
BIOLOGIA
url http://hdl.handle.net/20.500.14066/2997

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