Phytochemical and pharmacological aspects of the genus Chamaecrista : a systematic review

Corresponding Author: Juliana Moura-Mendes, Multidisciplinary Center for Technological Research, National University of Asunción, San Lorenzo, Paraguay. E-mail: jmendes@rec.una.py.

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Hoofdauteur: Villalba Fariña, Domitila (author)
Andere auteurs: Escobar Ávalos, Melissa Mariel (author), Cazal Martínez, Cinthia Carolina (author), Barúa Chamorro, Javier Enrique (author), de Oliveira Pereira, Fillipe (author), Moura Mendes Arrúa, Juliana (author)
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Taal:Engels
Gepubliceerd in: 2025
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Online toegang:https://doi.org/10.7324/JAPS.2025.241066
http://hdl.handle.net/20.500.14066/4711
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author Villalba Fariña, Domitila
author2 Escobar Ávalos, Melissa Mariel
Cazal Martínez, Cinthia Carolina
Barúa Chamorro, Javier Enrique
de Oliveira Pereira, Fillipe
Moura Mendes Arrúa, Juliana
author2_role author
author
author
author
author
author_browse Barúa Chamorro, Javier Enrique
Cazal Martínez, Cinthia Carolina
Escobar Ávalos, Melissa Mariel
Moura Mendes Arrúa, Juliana
Villalba Fariña, Domitila
de Oliveira Pereira, Fillipe
author_facet Villalba Fariña, Domitila
Escobar Ávalos, Melissa Mariel
Cazal Martínez, Cinthia Carolina
Barúa Chamorro, Javier Enrique
de Oliveira Pereira, Fillipe
Moura Mendes Arrúa, Juliana
author_role author
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dc.contributor.other.es.fl_str_mv Universidad Nacional de Asunción. Centro Multidisciplinario de Investigaciones Tecnológicas
dc.creator.none.fl_str_mv Villalba Fariña, Domitila
Escobar Ávalos, Melissa Mariel
Cazal Martínez, Cinthia Carolina
Barúa Chamorro, Javier Enrique
de Oliveira Pereira, Fillipe
Moura Mendes Arrúa, Juliana
dc.date.accessioned.none.fl_str_mv 2025-12-17T13:00:23Z
dc.date.available.none.fl_str_mv 2025-12-17T13:00:23Z
dc.date.issued.none.fl_str_mv 2025-12-05
dc.identifier.citation.en.fl_str_mv Villalba, D., Escobar, M., Cazal Martínez, C., Barúa, J. E., De Oliveira Pereira, F, & Moura Mendes, J. (2025). Phytochemical and pharmacological aspects of the genus Chamaecrista: a systematic review. Journal of Applied Pharmaceutical Science, 16(01), 005-028. https://doi.org/10.7324/JAPS.2025.241066
dc.identifier.doi.es.fl_str_mv 10.7324/JAPS.2025.241066
dc.identifier.essn.es.fl_str_mv 2231-3354
dc.identifier.other.es.fl_str_mv https://doi.org/10.7324/JAPS.2025.241066
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.14066/4711
dc.language.iso.es.fl_str_mv eng
dc.publisher.es.fl_str_mv Open Science Publishers LLP
dc.relation.projectCONACYT.es.fl_str_mv PINV01-91
dc.rights.*.fl_str_mv Atribución/Reconocimiento 4.0 Internacional
dc.rights.accessRights.es.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.uri.*.fl_str_mv http://creativecommons.org/licenses/by/4.0/
dc.subject.classification.es.fl_str_mv 7. Salud
7.2. Abarca desde medicina preventiva, incluyendo todos los aspectos de tratamientos médicos y quirúrgicos, tanto para individuos como para grupos, y las provisiones de hospitales y cuidado domiciliario, medicina social e investigación pediátrica y geriátrica
dc.subject.ocde.es.fl_str_mv 3. Ciencias Médicas y de la Salud
3.1. Medicina Básica (anatomía, citología, fisiología, genética, farmacia, farmacología, toxicología, inmunología e inmunohematología, química clínica, microbiología clínica, patología)
dc.subject.other.es.fl_str_mv Antioxidants
Fabaceae
Flavonoids
Medicinal plants
Senna
dc.title.es.fl_str_mv Phytochemical and pharmacological aspects of the genus Chamaecrista : a systematic review
dc.type.es.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
description Corresponding Author: Juliana Moura-Mendes, Multidisciplinary Center for Technological Research, National University of Asunción, San Lorenzo, Paraguay. E-mail: jmendes@rec.una.py.
eu_rights_str_mv openAccess
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identifier_str_mv Villalba, D., Escobar, M., Cazal Martínez, C., Barúa, J. E., De Oliveira Pereira, F, & Moura Mendes, J. (2025). Phytochemical and pharmacological aspects of the genus Chamaecrista: a systematic review. Journal of Applied Pharmaceutical Science, 16(01), 005-028. https://doi.org/10.7324/JAPS.2025.241066
10.7324/JAPS.2025.241066
2231-3354
language eng
network_acronym_str CONACYT
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publishDate 2025
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repository.name.fl_str_mv Repositorio Institucional CONACYT
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rights_invalid_str_mv Atribución/Reconocimiento 4.0 Internacional
http://creativecommons.org/licenses/by/4.0/
spelling 13576005f4143c5-6f78-4f94-a7d2-73d1e57affee60027560013460076c319e4-c8a3-4197-8608-eb2390ae3258600791600Universidad Nacional de Asunción. Centro Multidisciplinario de Investigaciones Tecnológicas2025-12-17T13:00:23Z2025-12-17T13:00:23Z2025-12-05Villalba, D., Escobar, M., Cazal Martínez, C., Barúa, J. E., De Oliveira Pereira, F, & Moura Mendes, J. (2025). Phytochemical and pharmacological aspects of the genus Chamaecrista: a systematic review. Journal of Applied Pharmaceutical Science, 16(01), 005-028. https://doi.org/10.7324/JAPS.2025.241066https://doi.org/10.7324/JAPS.2025.241066http://hdl.handle.net/20.500.14066/471110.7324/JAPS.2025.2410662231-3354Corresponding Author: Juliana Moura-Mendes, Multidisciplinary Center for Technological Research, National University of Asunción, San Lorenzo, Paraguay. E-mail: jmendes@rec.una.py.The genus Chamaecrista, belonging to the family Fabaceae, is mainly distributed in the American continent and is of great interest because of its extensive use in traditional medicine. This article presents a systematic review of the pharmacological and chemical properties of the Chamaecrista. Articles published between 2004 and 2023 were grouped through searches in the following databases: PubMed, SciELO, Scopus, Science Direct, Web of Science, and Google Scholar. Articles were included based on the selection and classification of titles and abstracts if they indicated the country of origin of the studies, plant species studied, compounds identified, and associated pharmacological activities. The results showed that most of the studies conducted in Brazil represented 35% of the published works. Moreover, Chamaecrista nictitans and Chamaecrista duckeana have been the most studied for their pharmacological potential, especially for their antioxidant activity. In addition, flavonoids were the leading group described, obtained from different extracts of various parts of the plant, with leaves being the most utilized. Despite promising advances in understanding the chemical composition and pharmacological properties of the genus Chamaecrista, this review highlights that no preclinical in vivo and clinical studies have been reported. This study underscores the importance of continuing research to identify and isolate new bioactive molecules from this genus, aiming to elucidate their pharmacological functions and potential therapeutic applications.Consejo Nacional de Ciencia y TecnologíaPrograma Paraguayo para el Desarrollo de la Ciencia y Tecnología. Proyectos de investigación y desarrolloengOpen Science Publishers LLPAtribución/Reconocimiento 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccess© 2026 Domitila Villalba et al. This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (https:// creativecommons.org/licenses/by/4.0/).7. Salud7.2. Abarca desde medicina preventiva, incluyendo todos los aspectos de tratamientos médicos y quirúrgicos, tanto para individuos como para grupos, y las provisiones de hospitales y cuidado domiciliario, medicina social e investigación pediátrica y geriátricaAntioxidantsFabaceaeFlavonoidsMedicinal plantsSenna3. Ciencias Médicas y de la Salud3.1. Medicina Básica (anatomía, citología, fisiología, genética, farmacia, farmacología, toxicología, inmunología e inmunohematología, química clínica, microbiología clínica, patología)Phytochemical and pharmacological aspects of the genus Chamaecrista : a systematic reviewinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion1Journal of Applied Pharmaceutical Science005028PINV01-9116Villalba Fariña, DomitilaEscobar Ávalos, Melissa MarielCazal Martínez, Cinthia CarolinaBarúa Chamorro, Javier Enriquede Oliveira Pereira, FillipeMoura Mendes Arrúa, JulianaORIGINALPhytochemical and pharmacological aspects of the genus Chamaecrista a systematic review.pdfPhytochemical and pharmacological aspects of the genus Chamaecrista a systematic review.pdfArtículo científicoapplication/pdf1759569http://repositorio.conacyt.gov.py/bitstream/20.500.14066/4711/1/Phytochemical%20and%20pharmacological%20aspects%20of%20the%20genus%20Chamaecrista%20a%20systematic%20review.pdfbe0b69415b0547a0fc6b7bfe4032347fMD51Supplementary material.pdfSupplementary material.pdfMaterial complementarioapplication/pdf421635http://repositorio.conacyt.gov.py/bitstream/20.500.14066/4711/4/Supplementary%20material.pdfe47a8dadbddd340d4dfe5cc458371199MD54CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; 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spellingShingle Phytochemical and pharmacological aspects of the genus Chamaecrista : a systematic review
Villalba Fariña, Domitila
7. Salud
7.2. Abarca desde medicina preventiva, incluyendo todos los aspectos de tratamientos médicos y quirúrgicos, tanto para individuos como para grupos, y las provisiones de hospitales y cuidado domiciliario, medicina social e investigación pediátrica y geriátrica
Antioxidants
Fabaceae
Flavonoids
Medicinal plants
Senna
3. Ciencias Médicas y de la Salud
3.1. Medicina Básica (anatomía, citología, fisiología, genética, farmacia, farmacología, toxicología, inmunología e inmunohematología, química clínica, microbiología clínica, patología)
status_str publishedVersion
title Phytochemical and pharmacological aspects of the genus Chamaecrista : a systematic review
title_full Phytochemical and pharmacological aspects of the genus Chamaecrista : a systematic review
title_fullStr Phytochemical and pharmacological aspects of the genus Chamaecrista : a systematic review
title_full_unstemmed Phytochemical and pharmacological aspects of the genus Chamaecrista : a systematic review
title_short Phytochemical and pharmacological aspects of the genus Chamaecrista : a systematic review
title_sort Phytochemical and pharmacological aspects of the genus Chamaecrista : a systematic review
topic 7. Salud
7.2. Abarca desde medicina preventiva, incluyendo todos los aspectos de tratamientos médicos y quirúrgicos, tanto para individuos como para grupos, y las provisiones de hospitales y cuidado domiciliario, medicina social e investigación pediátrica y geriátrica
Antioxidants
Fabaceae
Flavonoids
Medicinal plants
Senna
3. Ciencias Médicas y de la Salud
3.1. Medicina Básica (anatomía, citología, fisiología, genética, farmacia, farmacología, toxicología, inmunología e inmunohematología, química clínica, microbiología clínica, patología)
url https://doi.org/10.7324/JAPS.2025.241066
http://hdl.handle.net/20.500.14066/4711