Drug cocktail selection for the treatment of Chagas disease : a multi-objective approach

Chagas disease is a parasitic disease, endemic in South America. As of today, there is no effective treatment in its chronic stage. We have recently identified 134 FDA approved drugs with potential antitrypanosomal activity. In this paper, we propose a novel method for selecting combinations of drug...

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Bibliografiske detaljer

Hovedforfatter:	Torres, Mateo (author)
Andre forfattere:	Cáceres Silva, Juan José (author), Jiménez, Rubén (author), Yubero Rodríguez, Víctor Andrés (author), Vega Gómez, María Celeste (author), Rolón, Miriam Soledad (author), Cernuzzi, Luca Carlo (author), Barán, Benjamín (author), Burgos Edwards, Alberto Javier (author)
Format:	article
Sprog:	engelsk
Udgivet:	2017
Fag:	6. Producción y tecnología industrial Multi-objective optimisation Drug repurposing Chagas Disease Genetic Algorithms FARMACOLOGIA
Online adgang:	http://hdl.handle.net/20.500.14066/2831
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