Isolation and Antifouling Activity of Azulene Derivatives from the Antarctic Gorgonian Acanthogorgia laxa
Three azulenoid sesquiterpenes (1 – 3) were isolated from the Antarctic gorgonian Acanthogorgia laxa collected by bottom trawls at 343 m. Besides linderazulene (1), and the known ketolactone 2, a new brominated C16 linderazulene derivative (3) was also identified. This compound has an extra carbon a...
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| Format: | article |
| Jezik: | engleski |
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2017
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| Online pristup: | http://jadimike.unachi.ac.pa/handle/123456789/125 |
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| author | Patiño Cano, Laura Patricia |
| author2 | Quintana Manfredi, Rodrigo Pérez, Miriam García, Mónica Blustein, Guillermo Cordeiro, Ralf Pérez, Carlos D. Schejter, Laura Palermo, Jorge A. |
| author2_role | author author author author author author author author |
| author_browse | Blustein, Guillermo Cordeiro, Ralf García, Mónica Palermo, Jorge A. Patiño Cano, Laura Patricia Pérez, Carlos D. Pérez, Miriam Quintana Manfredi, Rodrigo Schejter, Laura |
| author_facet | Patiño Cano, Laura Patricia Quintana Manfredi, Rodrigo Pérez, Miriam García, Mónica Blustein, Guillermo Cordeiro, Ralf Pérez, Carlos D. Schejter, Laura Palermo, Jorge A. |
| author_role | author |
| collection | Repositorio JaDimike |
| dc.creator.none.fl_str_mv | Patiño Cano, Laura Patricia Quintana Manfredi, Rodrigo Pérez, Miriam García, Mónica Blustein, Guillermo Cordeiro, Ralf Pérez, Carlos D. Schejter, Laura Palermo, Jorge A. |
| dc.date.none.fl_str_mv | 2017 2019-09-10T13:32:13Z 2019-09-10T13:32:13Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | DOI: 10.1002/cbdv.201700425 http://jadimike.unachi.ac.pa/handle/123456789/125 |
| dc.language.none.fl_str_mv | eng en |
| dc.relation.none.fl_str_mv | none Chemistry & Biodiversity; |
| dc.rights.none.fl_str_mv | info:eu-repo/semantics/openAccess |
| dc.source.none.fl_str_mv | reponame:Repositorio JaDimike instname:Universidad Autónoma de Chiriquí instacron:UNACHI |
| dc.subject.none.fl_str_mv | octocorals Acanthogorgiidae marine natural products azulene sesquiterpenoids antifouling activity |
| dc.title.none.fl_str_mv | Isolation and Antifouling Activity of Azulene Derivatives from the Antarctic Gorgonian Acanthogorgia laxa |
| dc.type.none.fl_str_mv | info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| description | Three azulenoid sesquiterpenes (1 – 3) were isolated from the Antarctic gorgonian Acanthogorgia laxa collected by bottom trawls at 343 m. Besides linderazulene (1), and the known ketolactone 2, a new brominated C16 linderazulene derivative (3) was also identified. This compound has an extra carbon atom at C(7) of the linderazulene framework. The antifouling activity of compounds 1 and 2 was assayed in the laboratory with Artemia salina larvae, and also in field tests, by incorporation in soluble-matrix experimental antifouling paints. The results obtained after a 45 days field trial of the paints, showed that compounds 1 and 2 displayed good antifouling potencies against a wide array of organisms. Compound 3, a benzylic bromide, was unstable and for this reason was not submitted to bioassays. Two known cembranolides: pukalide and epoxypukalide, were also identified as minor components of the extract. |
| eu_rights_str_mv | openAccess |
| format | article |
| id | lrtest_abcf15bfafbc13198c148ceb9bfad21e |
| identifier_str_mv | DOI: 10.1002/cbdv.201700425 |
| instacron_str | UNACHI |
| institution | UNACHI |
| instname_str | Universidad Autónoma de Chiriquí |
| language | eng |
| language_invalid_str_mv | en |
| network_acronym_str | lrtest |
| network_name_str | lr |
| oai_identifier_str | oai:jadimike.unachi.ac.pa:123456789/125 |
| publishDate | 2017 |
| publishDateSort | 2017 |
| reponame_str | Repositorio JaDimike |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| spelling | Isolation and Antifouling Activity of Azulene Derivatives from the Antarctic Gorgonian Acanthogorgia laxaPatiño Cano, Laura PatriciaQuintana Manfredi, RodrigoPérez, MiriamGarcía, MónicaBlustein, GuillermoCordeiro, RalfPérez, Carlos D.Schejter, LauraPalermo, Jorge A.octocoralsAcanthogorgiidaemarine natural productsazulene sesquiterpenoidsantifouling activityThree azulenoid sesquiterpenes (1 – 3) were isolated from the Antarctic gorgonian Acanthogorgia laxa collected by bottom trawls at 343 m. Besides linderazulene (1), and the known ketolactone 2, a new brominated C16 linderazulene derivative (3) was also identified. This compound has an extra carbon atom at C(7) of the linderazulene framework. The antifouling activity of compounds 1 and 2 was assayed in the laboratory with Artemia salina larvae, and also in field tests, by incorporation in soluble-matrix experimental antifouling paints. The results obtained after a 45 days field trial of the paints, showed that compounds 1 and 2 displayed good antifouling potencies against a wide array of organisms. Compound 3, a benzylic bromide, was unstable and for this reason was not submitted to bioassays. Two known cembranolides: pukalide and epoxypukalide, were also identified as minor components of the extract.Three azulenoid sesquiterpenes (1 – 3) were isolated from the Antarctic gorgonian Acanthogorgia laxa collected by bottom trawls at 343 m. Besides linderazulene (1), and the known ketolactone 2, a new brominated C16 linderazulene derivative (3) was also identified. This compound has an extra carbon atom at C(7) of the linderazulene framework. The antifouling activity of compounds 1 and 2 was assayed in the laboratory with Artemia salina larvae, and also in field tests, by incorporation in soluble-matrix experimental antifouling paints. The results obtained after a 45 days field trial of the paints, showed that compounds 1 and 2 displayed good antifouling potencies against a wide array of organisms. Compound 3, a benzylic bromide, was unstable and for this reason was not submitted to bioassays. Two known cembranolides: pukalide and epoxypukalide, were also identified as minor components of the extract.2019-09-10T13:32:13Z2019-09-10T13:32:13Z2017info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfDOI: 10.1002/cbdv.201700425http://jadimike.unachi.ac.pa/handle/123456789/125engennoneChemistry & Biodiversity;info:eu-repo/semantics/openAccessreponame:Repositorio JaDimikeinstname:Universidad Autónoma de Chiriquíinstacron:UNACHIoai:jadimike.unachi.ac.pa:123456789/1252019-10-16T15:11:41Z |
| spellingShingle | Isolation and Antifouling Activity of Azulene Derivatives from the Antarctic Gorgonian Acanthogorgia laxa Patiño Cano, Laura Patricia octocorals Acanthogorgiidae marine natural products azulene sesquiterpenoids antifouling activity |
| status_str | publishedVersion |
| title | Isolation and Antifouling Activity of Azulene Derivatives from the Antarctic Gorgonian Acanthogorgia laxa |
| title_full | Isolation and Antifouling Activity of Azulene Derivatives from the Antarctic Gorgonian Acanthogorgia laxa |
| title_fullStr | Isolation and Antifouling Activity of Azulene Derivatives from the Antarctic Gorgonian Acanthogorgia laxa |
| title_full_unstemmed | Isolation and Antifouling Activity of Azulene Derivatives from the Antarctic Gorgonian Acanthogorgia laxa |
| title_short | Isolation and Antifouling Activity of Azulene Derivatives from the Antarctic Gorgonian Acanthogorgia laxa |
| title_sort | Isolation and Antifouling Activity of Azulene Derivatives from the Antarctic Gorgonian Acanthogorgia laxa |
| topic | octocorals Acanthogorgiidae marine natural products azulene sesquiterpenoids antifouling activity |
| url | http://jadimike.unachi.ac.pa/handle/123456789/125 |