Changes in the topology of DNA replication intermediates: Important discrepancies between in vitro and in vivo

The topology of DNA duplexes changes during replication and also after deproteinization in vitro. Here we describe these changes and then discuss for the first time how the distribution of superhelical stress affects the DNA topology of replication intermediates, taking into account the progression...

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Bibliographic Details

Main Author:	Schvartzman, Jorge Bernardo (author)
Other Authors:	Martínez, Víctor (author), Hernández, Pablo (author), Krimer, Dora B. (author), Fernández de Nestosa, María José (author)
Format:	article
Language:	English
Published:	2021
Subjects:	7. Salud CATENATION DNA CHIRALITY DNA TOPOLOGY PRE-CATENATION REPLICATION SUPERCOILING
Online Access:	http://hdl.handle.net/20.500.14066/3833 https://doi.org/10.1002/bies.202000309
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