Propiedades conformacionales y energéticas de los intermediarios de replicación de DNA circular

DNA topology changes continuously as replication proceeds. Unwinding of the DNA duplex by helicases is favored by negative supercoiling but it causes the progressive accumulation of positive supercoiling ahead of the replication forks. In covalent closed circular DNA molecules this torsional stress...

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Bibliografiske detaljer
Hovedforfatter: Martínez Chamorro, Víctor Manuel (author)
Format: doctoralThesis
Sprog:spansk
Udgivet: 2020
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Online adgang:http://hdl.handle.net/20.500.14066/2931
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