Propiedades conformacionales y energéticas de los intermediarios de replicación de DNA circular

DNA topology changes continuously as replication proceeds. Unwinding of the DNA duplex by helicases is favored by negative supercoiling but it causes the progressive accumulation of positive supercoiling ahead of the replication forks. In covalent closed circular DNA molecules this torsional stress...

ver descrição completa

Detalhes bibliográficos

Autor principal:	Martínez Chamorro, Víctor Manuel (author)
Formato:	doctoralThesis
Idioma:	espanhol
Publicado em:	2020
Assuntos:	1303 I+D en relación con las ciencias médicas ADN circular Biología computacional Método de Montecarlo Replicación del ADN Simulación por computador Termodinámica DNA, circular Computational biology Monte Carlo Method DNA replication Computer simulation Thermodynamics
Acesso em linha:	http://hdl.handle.net/20.500.14066/2931
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!